 |
 |
|
|
|
|
|
|
|
|
|
||||
|
|
|
|
|
||||
|
MetGen develops and produces Laccases tailored to the industrial customer needs.
Laccases are enzymes belonging to the multicopper oxidases class. These enzymes are involved in several oxidative functions and particularly in delignification.
MetGen addresses the needs of the following industries. Pulp & Paper Industry: Laccases are able to delignify wood pulp by an oxidation chain reaction leading to lignin oxidation respecting the integrity of cellulose. Laccase are also used in biopulping which is applicable to both mechanical and chemical pulps. Advantages of using laccase mediator system (LMS) in biopulping results in reduction of refining energy, increase of mill throughput in mechanical pulping, enhanced paper strength properties, reduction of pitch problems, improved yield, and reduced environmental impact. Biofuel and Biorefinery: Lignin strongly prevents the conversion yield of polysaccharides to bioethanol. MetGen's laccase disrupt the lignin network and thereby facilitate the interaction between enzymes and polysaccharides. Laccase treatment improves bioconversion of lignocellulosic biomass into biofuels. Waste Water Treatment: In spite of the variety of methods used for wastewater treatment, remaining wastes are maintaining high COD and phenol levels. Lignin is a major contributor high level of COD. MetGen's laccase is affordable way to remove lignin from waste waters. MetGen developed proprietary technology platform to modify enzymes properties by mutations of their amino acid sequence in order to increase their activity and fit the conditions required by industry (pH, temperature, solvents tolerance). An intelligent design of mutations to be introduced within the sequence and a subsequent screen of the various mutants in industrial conditions permit the selection of the best clone to be produced in large scale and implemented in the industrial process. MetGen is also developing custom biotransformation processes for small molecule drugs ( i.e modified nucleosides) or protein molecules with high affinity to specific bio-molecules (i.e synthetic therapeutic antibodies, inhibitory peptides). MetGen already achieved notable success in the discovery, development and commercialization of specialty enzymes for the paper and pulp, waste water treatment, pharma and biofuel industries. Continuing to build on this expertise, MetGen provides unique enzymes for its customers.  |
|
||||||||||||||||||||||
